Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370810 | 0.90 | L3MBTL1 (0.52) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL8814928 | 0.86 | NPC1 (0.46) | MEN1KMT2AL3MBTL1HDAC7LMNA | |
| SCHEMBL8816546 | 0.80 | CYP19A1 (0.45) | MEN1KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL8812526 | 0.78 | GCGR (0.40) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL8813868 | 0.77 | MEN1 (0.37) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL8814391 | 0.76 | POLB (0.46) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL7377166 | 0.75 | AVPR2 (0.48) | MEN1KMT2AL3MBTL1LMNAGPR27 | |
| SCHEMBL7371083 | 0.73 | HTT (0.56) | KMT2AL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL1458777 | 0.72 | CHRNB2 (0.63) | MEN1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL2960788 | 0.71 | CHRNB2 (0.61) | L3MBTL1POLBALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |