Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377166 | 0.90 | AVPR2 (0.48) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL8814391 | 0.89 | POLB (0.46) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL8812976 | 0.86 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL8816546 | 0.86 | CYP19A1 (0.45) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL8812526 | 0.83 | GCGR (0.40) | MEN1KMT2AL3MBTL1TP53MAPT | |
| SCHEMBL8812136 | 0.83 | SMN1; SMN2 (0.46) | NPC1RAB9ATP53PPARGPPARA | |
| SCHEMBL8813752 | 0.80 | KCNMA1 (0.49) | NPC1MEN1KMT2ATP53MAPT | |
| SCHEMBL7367409 | 0.79 | HTT (0.47) | NPC1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7376165 | 0.79 | AVPR2 (0.48) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL7512593 | 0.77 | CYP19A1 (0.45) | NPC1RAB9AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |