Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814928 | 0.90 | NPC1 (0.46) | NPC1RAB9AL3MBTL1LMNAKMT2A | |
| SCHEMBL7376165 | 0.89 | AVPR2 (0.48) | AVPR2AVPR1ANPC1RAB9AL3MBTL1 | |
| SCHEMBL7367409 | 0.89 | HTT (0.47) | NPC1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL7370810 | 0.85 | L3MBTL1 (0.52) | AVPR2AVPR1AL3MBTL1LMNAKMT2A | |
| SCHEMBL7512593 | 0.85 | CYP19A1 (0.45) | AVPR2AVPR1ANPC1RAB9AL3MBTL1 | |
| SCHEMBL7513968 | 0.84 | RAB9A (0.46) | AVPR2AVPR1ANPC1RAB9ALMNA | |
| SCHEMBL7373393 | 0.82 | ALDH1A1 (0.47) | AVPR2AVPR1ANPC1RAB9ATP53 | |
| SCHEMBL7370671 | 0.82 | GCGR (0.41) | AVPR2AVPR1AL3MBTL1KMT2AMEN1 | |
| SCHEMBL7376778 | 0.81 | NPC1 (0.51) | NPC1RAB9AL3MBTL1LMNAKMT2A | |
| SCHEMBL7374161 | 0.80 | AVPR2 (0.40) | AVPR2AVPR1ALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |