Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812976 | 0.90 | MEN1 (0.51) | L3MBTL1POLBLMNAMEN1KMT2A | |
| SCHEMBL7377166 | 0.85 | AVPR2 (0.48) | L3MBTL1LMNAMEN1KMT2ATP53 | |
| SCHEMBL7371083 | 0.85 | HTT (0.56) | L3MBTL1POLBLMNAKMT2ATP53 | |
| SCHEMBL7378335 | 0.81 | CHRNB2 (0.52) | L3MBTL1POLBLMNAKMT2ATP53 | |
| SCHEMBL7517678 | 0.81 | NPC1 (0.47) | L3MBTL1POLBLMNAKMT2ATP53 | |
| SCHEMBL7376298 | 0.80 | L3MBTL1 (0.48) | L3MBTL1POLBLMNAKMT2ATP53 | |
| SCHEMBL7512593 | 0.80 | CYP19A1 (0.45) | L3MBTL1MEN1KMT2ATP53AVPR2 | |
| SCHEMBL7374840 | 0.79 | PYGL (0.41) | L3MBTL1LMNAMEN1KMT2AAVPR2 | |
| SCHEMBL7368408 | 0.79 | HSD17B1 (0.58) | L3MBTL1POLBLMNAKMT2ATP53 | |
| SCHEMBL7370671 | 0.78 | GCGR (0.41) | L3MBTL1POLBMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |