SCHEMBL8816352

SCHEMBL8816352

Cc1nc2c(O)cccn2c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
GAA P10253 2/20 0.53
LMNA P02545 1/20 0.53
GLA P06280 1/20 0.53
MPI P34949 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR1A P08908 1/20 0.38
DRD2 P14416 1/20 0.38
HTR2A P28223 1/20 0.38
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7013857 0.84 KDM4E (0.51) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL4063787 0.83 ALDH1A1 (0.54) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL17028868 0.79 ALDH1A1 (0.50) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL8813632 0.78 ATP4A (0.41) ALDH1A1KDM4EGAAGLASMN1; SMN2
SCHEMBL10435571 0.77 ALDH1A1 (0.49) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL7016018 0.77 ALDH1A1 (0.56) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL5634105 0.77 ATP4A (0.57) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL7510044 0.76 ALDH1A1 (0.51) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL9286867 0.76 ALDH1A1 (0.54) ALDH1A1KDM4EGAALMNAGLA
SCHEMBL8317131 0.74 ALDH1A1 (0.46) ALDH1A1KDM4EGAALMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0772614-A1 HALOGENATED IMIDAZOPYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1997-05-14 EP disclosed
WO-1996003402-A1 HALOGENATED IMIDAZOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1996-02-08 WO disclosed