Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.36 |
| ▸ | POLRMT | O00411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881457 | 0.81 | TMPRSS2 (0.34) | RIPK1 | |
| SCHEMBL881450 | 0.81 | ADORA2A (0.33) | RIPK1POLRMT | |
| SCHEMBL15682881 | 0.78 | TMPRSS2 (0.35) | POLRMT | |
| SCHEMBL12243243 | 0.78 | ADORA2A (0.36) | POLRMT | |
| SCHEMBL12393214 | 0.78 | ADORA2A (0.36) | POLRMT | |
| SCHEMBL18697868 | 0.76 | RIPK1 (0.31) | RIPK1POLRMT | |
| SCHEMBL10154383 | 0.75 | RIPK1 (0.31) | RIPK1POLRMT | |
| SCHEMBL23047661 | 0.75 | ACVRL1 (0.32) | RIPK1POLRMT | |
| SCHEMBL18666834 | 0.75 | ACVRL1 (0.32) | RIPK1POLRMT | |
| SCHEMBL807536 | 0.75 | ACVRL1 (0.32) | RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |