Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882530 | 0.81 | TMPRSS2 (0.41) | — | |
| SCHEMBL12393252 | 0.79 | TMPRSS2 (0.40) | RIPK1POLRMT | |
| SCHEMBL23047633 | 0.78 | POLRMT (0.32) | POLRMT | |
| SCHEMBL18666916 | 0.78 | POLRMT (0.32) | POLRMT | |
| SCHEMBL10154383 | 0.77 | RIPK1 (0.31) | RIPK1POLRMT | |
| SCHEMBL881706 | 0.76 | RIPK1 (0.36) | RIPK1POLRMT | |
| SCHEMBL807536 | 0.74 | ACVRL1 (0.32) | RIPK1POLRMT | |
| SCHEMBL23047661 | 0.74 | ACVRL1 (0.32) | RIPK1POLRMT | |
| SCHEMBL18666834 | 0.74 | ACVRL1 (0.32) | RIPK1POLRMT | |
| SCHEMBL24058362 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150608-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |