Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.32 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19756730 | 0.72 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3CHRNA7HTR3A | |
| SCHEMBL28905147 | 0.71 | L3MBTL1 (0.51) | SLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL7138055 | 0.70 | MAPT (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6573927 | 0.69 | PPARD (0.32) | — | |
| SCHEMBL8976942 | 0.67 | PRCP (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL655217 | 0.67 | HTR3A (0.43) | SLC6A2SLC6A4SLC6A3CHRNA7HTR3A | |
| SCHEMBL4169709 | 0.67 | SLC18A3 (0.42) | SLC6A2SLC6A4GID4 | |
| SCHEMBL7416329 | 0.66 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL4470943 | 0.66 | HTR3A (0.42) | SLC6A2SLC6A4SLC6A3CHRNA7HTR3A | |
| SCHEMBL5584370 | 0.66 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047302-A1 | INHIBITION OF SEROTONIN REUPTAKE | ELI LILLY AND COMPANY (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |