Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820211 | 0.80 | ADRA1A (0.33) | ALDH1A1ACE | |
| SCHEMBL8820260 | 0.78 | USP2 (0.33) | ALDH1A1LMNASMN1; SMN2ACE | |
| SCHEMBL8817416 | 0.77 | ALDH1A1 (0.33) | ALDH1A1ACE | |
| SCHEMBL8817341 | 0.75 | ADORA3 (0.38) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL8817390 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8817363 | 0.73 | TNKS2 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8819028 | 0.72 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL8932451 | 0.71 | GAA (0.35) | SMN1; SMN2ACE | |
| SCHEMBL8820385 | 0.71 | ACE (0.33) | ALDH1A1ACE | |
| SCHEMBL13042918 | 0.64 | RAB9A (0.47) | ALDH1A1SMN1; SMN2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033888-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-18 | — | — | WO | disclosed |