SCHEMBL8820385

SCHEMBL8820385

O=C(SC1CSc2cnnn2C1)c1ccccc1.OC1CSc2cnnn2C1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HSD11B1 P28845 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817390 0.81 ALDH1A1 (0.36) ALDH1A1HSD11B1
SCHEMBL8932640 0.71 CTSL (0.32) ALDH1A1
SCHEMBL8820263 0.71 KDM4E (0.33) ACEALDH1A1
SCHEMBL8820260 0.69 USP2 (0.33) ACEALDH1A1
SCHEMBL8817416 0.68 ALDH1A1 (0.33) ACEALDH1A1
SCHEMBL8932451 0.68 GAA (0.35) ACE
SCHEMBL8820211 0.66 ADRA1A (0.33) ACEALDH1A1
SCHEMBL8817363 0.65 TNKS2 (0.41) ALDH1A1
SCHEMBL8932630 0.64 CHRNB2 (0.32) ALDH1A1
SCHEMBL8819028 0.64 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033888-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-18 WO disclosed