Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833717 | 0.86 | CA2 (0.49) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL11407805 | 0.84 | CA2 (0.63) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL10422318 | 0.83 | SLC25A1 (0.66) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL23832738 | 0.83 | CA12 (0.61) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL7572373 | 0.83 | L3MBTL1 (0.67) | CA2CA12CA9MAPTMEN1 | |
| SCHEMBL34474379 | 0.82 | MYC (0.52) | CA2CA12CA9MCL1MAPT | |
| SCHEMBL7015594 | 0.81 | GUSB (0.66) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL2741009 | 0.81 | CA2 (0.58) | CA2CA12CA9BCL2L1MCL1 | |
| SCHEMBL25754684 | 0.80 | HPGD (0.62) | CA2CA12CA9MAPTMEN1 | |
| SCHEMBL2912639 | 0.78 | CA2 (0.51) | CA2CA12CA9MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046520-A1 | 4-NITRO-2-PHENOXYSULFONANILIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-11 | — | — | WO | disclosed |