Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823098 | 0.84 | GABRA2 (0.51) | HSD11B1 | |
| SCHEMBL274962 | 0.81 | HSD11B1 (0.58) | HSD11B1KMT2APTGER1CYP2A6 | |
| SCHEMBL8823114 | 0.80 | ALDH1A1 (0.49) | MDM2KMT2AMEN1 | |
| SCHEMBL19356980 | 0.79 | HSD11B1 (0.53) | HSD11B1KMT2AMEN1 | |
| SCHEMBL8823172 | 0.79 | KDM4E (0.50) | HSD11B1MDM2KMT2A | |
| SCHEMBL8823133 | 0.79 | HSD11B1 (0.52) | HSD11B1KMT2ADHODHPTGER1P2RX7 | |
| SCHEMBL27548634 | 0.78 | HSD11B1 (0.46) | HSD11B1KMT2ADHODHP2RX7 | |
| SCHEMBL27508406 | 0.76 | HSD11B1 (0.49) | HSD11B1KMT2ADHODHPTGER1CYP2A6 | |
| SCHEMBL8823047 | 0.75 | ALDH1A1 (0.52) | KMT2AMEN1 | |
| SCHEMBL13499115 | 0.75 | KMT2A (0.47) | HSD11B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1153172-A | Azole derivatives, their use, production and usage | NIHON NOHYAKU CO LTD (JP) | 1997-07-02 | — | — | CN | disclosed |
| EP-0761658-A1 | Azole-phenyl urea derivatives as ACAT inhibitors and their production | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |