Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244255 | 0.88 | ALDH1A1 (0.76) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL10821063 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2LMNAMAPT | |
| SCHEMBL882483 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL289519 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL6266650 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL882714 | 0.80 | MAPT (0.57) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL2362831 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL244752 | 0.77 | ALDH1A1 (0.73) | ALDH1A1HPGDCYP1A2HSD17B10LMNA | |
| SCHEMBL874301 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HPGDCYP1A2HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL8114168 | 0.75 | ALDH1A1 (0.71) | ALDH1A1HPGDCYP1A2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2005041665-A1 | INSECTICIDAL PERFLUOROALKYLTHIAZOLE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | NIPPON SODA CO., LTD. | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | FFAR3, CYP4F3, NPFFR1 | ALDH1A1 1843/4885HPGD 3799/4885CYP1A2 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.