Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 7/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874572 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRMAPTRORB | |
| SCHEMBL10820841 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRMAPTNPC1 | |
| SCHEMBL874267 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL882389 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL874117 | 0.76 | RAB9A (0.48) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL8627631 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRMAPTNPC1 | |
| SCHEMBL874785 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL10820886 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRMAPTNPC1 | |
| SCHEMBL13066651 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRMAPTRORB | |
| SCHEMBL11330712 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTRORBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |