Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20087385 | 0.89 | TDP1 (0.40) | CA12CA14CA2TDP1CA1 | |
| SCHEMBL22615877 | 0.82 | APEX1 (0.37) | CA12CA14CA2TDP1CA1 | |
| SCHEMBL22145757 | 0.82 | CA12 (0.34) | CA12CA14CA2CA1CA7 | |
| SCHEMBL1843089 | 0.78 | CA12 (0.47) | CA12CA14CA2CA1CA7 | |
| SCHEMBL18776030 | 0.74 | CA12 (0.39) | CA12CA14CA2TDP1CA1 | |
| SCHEMBL10724862 | 0.74 | CA12 (0.39) | CA12CA14CA2TDP1CA1 | |
| SCHEMBL11232767 | 0.73 | GAA (0.44) | CA12CA2CA1 | |
| SCHEMBL882495 | 0.73 | THRB (0.40) | TDP1 | |
| SCHEMBL14483954 | 0.72 | CA2 (0.38) | CA12CA14CA2CA1CA7 | |
| SCHEMBL3451980 | 0.72 | CA12 (0.38) | CA12CA14CA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2618845-B1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B V (NL) | 2020-02-26 | — | — | EP | disclosed |
| US-9339554-B2 | Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith | CRISTAL DELIVERY B.V. (NL) | 2016-05-17 | — | — | US | disclosed |
| US-9339554-B2 | Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith | CRISTAL DELIVERY B.V. (NL) | 2016-05-17 | — | — | US | disclosed |
| US-9339554-B2 | Tunable, biodegradable linker molecules for transient conjugation of components in drug delivery systems, and drug delivery systems prepared therewith | CRISTAL DELIVERY B.V. (NL) | 2016-05-17 | — | — | US | disclosed |
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B.V. (NL) | 2013-10-03 | — | — | US | disclosed |
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B.V. (NL) | 2013-10-03 | — | — | US | disclosed |
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | CRISTAL DELIVERY B.V. (NL) | 2013-10-03 | — | — | US | disclosed |
| WO-2012039602-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261094-A1 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH | GSS, PFAS, ABCB1 | CA12 2116/4885CA14 2571/4885CA2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.