SCHEMBL22145757

SCHEMBL22145757

CC(C)(C)OC(=O)CS(=O)(=O)CCCl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA2 P00918 1/20 0.34
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL882497 0.82 CA12 (0.35) CA12CA14CA2CA1CA7
SCHEMBL20087385 0.79 TDP1 (0.40) CA12CA14CA2CA1CA7
SCHEMBL22345238 0.78 TSHR (0.41) CA12CA14CA2CA1CA7
SCHEMBL1843089 0.76 CA12 (0.47) CA12CA14CA2CA1CA7
SCHEMBL3451980 0.75 CA12 (0.38) CA12CA14CA2CA1CA7
SCHEMBL11226349 0.74 GAA (0.43) CA12CA2CA1
SCHEMBL10724862 0.73 CA12 (0.39) CA12CA14CA2CA1CA7
SCHEMBL18776030 0.73 CA12 (0.39) CA12CA14CA2CA1CA7
SCHEMBL882495 0.72 THRB (0.40)
SCHEMBL14483954 0.71 CA2 (0.38) CA12CA14CA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210285955-A1 METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES WARP DRIVE BIO, INC. 2021-09-16 US disclosed
US-20200199102-A1 COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF Revolution Medicines, Inc. 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210285955-A1 METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES FKBP8, PIN1, FKBP1A CA12 1472/4885CA14 876/4885CA2 1281/4885
US-20200199102-A1 COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF PIN1, FKBP14, FKBP2 CA12 3298/4885CA14 2936/4885CA2 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.