Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445279 | 0.82 | MMP8 (0.36) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL1597955 | 0.77 | SOAT1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL1444159 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL290478 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL3875800 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10HTTALOX15 | |
| SCHEMBL932895 | 0.74 | — | — | |
| SCHEMBL8971069 | 0.74 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10HTTALOX15 | |
| SCHEMBL1920127 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL882685 | 0.73 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10HTTALOX15 | |
| SCHEMBL28694430 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371950-B1 | Substituted thiazoles and their use as fungicides | MONSANTO CO (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5045554-A | Fluoro compounds, rice sheath blight, Basidiomycetes type fungus | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0371950-A2 | Substituted thiazoles and their use as fungicides | Monsanto Company (US) | 1990-06-06 | — | — | EP | disclosed |