SCHEMBL8971069

SCHEMBL8971069

CCOC(=O)C(Cl)C(=O)C(F)(F)Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
KMT2A Q03164 2/20 0.33
ALOX15 P16050 1/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
TRPA1 O75762 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC4 P56524 2/20 0.31
HDAC6 Q9UBN7 2/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290478 0.86 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL28422244 0.83 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL882685 0.82 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL65116 0.79 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL9218455 0.78 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL1444159 0.78 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL9218462 0.74 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL15282009 0.74 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10KMT2A
SCHEMBL28694430 0.74 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10KMT2AALOX15
SCHEMBL9493851 0.72 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521145-A Iminothiazoline derivatives and herbicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1996-05-28 US disclosed
EP-0683160-A1 Iminothiazoline derivatives and herbicides containing them as active ingredients SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-22 EP disclosed