SCHEMBL28049157

SCHEMBL28049157

Cc1ccccc1NC(=O)OOC(=O)Nc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.58
NPC1 O15118 4/20 0.58
HPGD P15428 4/20 0.55
ALDH1A1 P00352 2/20 0.55
POLB P06746 1/20 0.54
DDX3X O00571 2/20 0.54
MAPT P10636 3/20 0.51
KMT2A Q03164 1/20 0.50
ITGB3 P05106 1/20 0.49
ITGB1 P05556 1/20 0.49
ITGAV P06756 1/20 0.49
ITGA5 P08648 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
PLA2G1B P04054 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ATG4B Q9Y4P1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8827353 0.83 SMN1; SMN2 (0.61) RAB9ANPC1HPGDALDH1A1MAPT
SCHEMBL812756 0.80 DDX3X (0.80) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL1720197 0.80 NPC1 (0.67) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL8177930 0.77 KMT2A (0.71) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL665339 0.77 RAB9A (0.75) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL2096115 0.77 NPC1 (0.62) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL28333317 0.76 SMN1; SMN2 (0.58) RAB9ANPC1HPGDALDH1A1POLB
Hydrochloric Acid SCHEMBL11453497 0.75 RAB9A (0.72) RAB9ANPC1HPGDALDH1A1POLB
SCHEMBL69360 0.75 NPC1 (0.71) RAB9ANPC1HPGDALDH1A1MAPT
SCHEMBL30593915 0.75 NPC1 (0.71) RAB9ANPC1HPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105143195-A Furfural derivatives as a vehicle RHODIA OPERATIONS 2015-12-09 CN disclosed