Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637396 | 0.74 | PTGES (0.36) | HRH4KDM4EGSK3AGSK3BDYRK1A | |
| SCHEMBL7367919 | 0.67 | MERTK (0.38) | MMP1MMP2MMP3NPC1RAB9A | |
| SCHEMBL8612392 | 0.66 | NR4A2 (0.33) | ALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL8872967 | 0.64 | TSHR (0.40) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL8828083 | 0.63 | MMP1 (0.42) | MMP1MMP2MMP3ALDH1A1KDM4E | |
| SCHEMBL8828095 | 0.61 | GRIN1 (0.49) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11651582 | 0.61 | ALDH1A1 (0.41) | RAB9AALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7675179 | 0.60 | HRH4 (0.56) | MMP1MMP2MMP3HRH4KMT2A | |
| SCHEMBL6306591 | 0.59 | HRH4 (0.60) | NPC1RAB9AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL5973850 | 0.59 | POLB (0.37) | HRH4KDM4EKMT2AMEN1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |