Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828418 | 0.85 | DRD2 (0.47) | DRD2HTR1ADRD3SMN1; SMN2DRD4 | |
| SCHEMBL8828510 | 0.82 | DRD2 (0.62) | DRD2HTR1ADRD3ADRA1ALMNA | |
| SCHEMBL16440177 | 0.79 | DRD2 (0.50) | DRD2NPC1RAB9AHTR1ADRD3 | |
| SCHEMBL8828450 | 0.78 | DRD2 (0.43) | DRD2HTR1ADRD3ADRA1ADRD4 | |
| SCHEMBL8828496 | 0.77 | DRD2 (0.44) | DRD2HTR1ADRD3HTR2ASMN1; SMN2 | |
| SCHEMBL8828555 | 0.77 | HTR3E (0.57) | DRD2HTR1AADRA1ALMNADRD4 | |
| SCHEMBL12082468 | 0.76 | DRD2 (0.62) | DRD2HTR1ADRD3HTR2AHTR7 | |
| SCHEMBL8342531 | 0.76 | ALDH1A1 (0.61) | DRD2HTR1ADRD3LMNAHTT | |
| SCHEMBL12385910 | 0.75 | ALDH1A1 (0.59) | HTR1ALMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28272519 | 0.74 | DRD2 (0.64) | DRD2HTR1ADRD3ADRA1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |