Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828418 | 0.90 | DRD2 (0.47) | DRD2MAPK1DRD3TSHRMEN1 | |
| SCHEMBL8828555 | 0.84 | HTR3E (0.57) | DRD2ALDH1A1HTR1A | |
| SCHEMBL8828510 | 0.83 | DRD2 (0.62) | DRD2MAPK1DRD3HTR6ALDH1A1 | |
| SCHEMBL8828413 | 0.78 | ALDH1A1 (0.39) | MAPK1DRD3TSHRMEN1KMT2A | |
| SCHEMBL8828459 | 0.77 | DRD2 (0.42) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL28272519 | 0.76 | DRD2 (0.64) | DRD2DRD3HTR6HTR1A | |
| SCHEMBL1267184 | 0.74 | HTR3E (0.45) | DRD2MAPK1DRD3HTR6TSHR | |
| SCHEMBL8828657 | 0.74 | ALDH1A1 (0.49) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8828439 | 0.74 | POLB (0.45) | MAPK1DRD3TSHRMEN1KMT2A | |
| SCHEMBL23102075 | 0.73 | POLB (0.50) | DRD2MAPK1DRD3HTR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |