SCHEMBL8829779

SCHEMBL8829779

CCO[Si](C)(OCC)OCC.CCO[Si](OCC)(OCC)C(CC)NC(=O)CCCC(N)=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
KMT2A Q03164 3/20 0.32
DNM1 Q05193 1/20 0.31
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447042 0.94 POLB (0.38) POLBKMT2ADNM1MEN1FAAH
SCHEMBL485763 0.81 KMT2A (0.36) POLBKMT2ADNM1MEN1FAAH
SCHEMBL7125613 0.81
SCHEMBL775222 0.80 FAAH (0.53) KMT2ADNM1MEN1FAAHMAPK1
SCHEMBL126477 0.75 CAD (0.39)
Methyl Alcohol SCHEMBL22551139 0.74 CAD (0.38)
SCHEMBL6551652 0.72 ALDH1A1 (0.38) MAPK1
SCHEMBL9223861 0.71 CTSK (0.40) KMT2A
SCHEMBL4561830 0.71 ALDH1A1 (0.32)
SCHEMBL8829782 0.70 TSHR (0.41) POLBKMT2ADNM1MEN1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624711-A AFFIXING FUNCTIONAL SITES TO THE SURFACE OF A SOLID SUBSTRATE AFFYMAX TECHNOLOGIES, N.V. (NL) 1997-04-29 US disclosed