SCHEMBL883030

SCHEMBL883030

COC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.54
NPC1 O15118 1/20 0.54
FKBP1A P62942 1/20 0.52
LMNA P02545 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
POLB P06746 1/20 0.51
UCHL1 P09936 2/20 0.48
SCN4A P35499 1/20 0.48
EPHX2 P34913 1/20 0.48
USP30 Q70CQ3 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
KLK7 P49862 1/20 0.47
PEPD P12955 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486184 1.00 HSD17B10 (0.58) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL190042 1.00 HSD17B10 (0.58) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
Hydrochloric Acid SCHEMBL29889454 0.98 HSD17B10 (0.57) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL2737884 0.95 FKBP1A (0.58) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL2898129 0.95 FKBP1A (0.58) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL88684 0.95 FKBP1A (0.58) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL6272597 0.94 HSD17B10 (0.60) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL3467497 0.94 HSD17B10 (0.60) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL6361642 0.94 HSD17B10 (0.60) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA
SCHEMBL18455416 0.94 FKBP1A (0.57) HSD17B10SMN1; SMN2NPC1FKBP1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505138-A Chiral covalent organic framework mimic enzyme catalyst and preparation method and application thereof 浙江工业大学 2025-02-25 CN claimed
CN-112121853-B Mesoporous hollow silica nanosphere loaded with prolinol catalyst as well as preparation method and application of mesoporous hollow silica nanosphere 重庆邮电大学 2023-03-28 CN claimed
CN-111057736-B Application of lipase in splitting BOC-DL-proline methyl ester 浙江工业大学 2022-03-18 CN claimed
CN-102166530-B Bi-chiral organic small molecular catalyst and preparation method thereof UNIV SHANGHAI 2013-03-06 CN claimed
CN-102166530-A Bi-chiral organic small molecular catalyst and preparation method thereof UNIV SHANGHAI 2011-08-31 CN claimed
EP-4107166-B1 HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
CN-122036924-A Synthetic method of bionic collagen hexapeptide 成都欣肽生物科技有限公司 2026-05-15 CN disclosed
EP-4709729-A1 PYRAZOLO[4,3-F]QUINAZOLINE DERIVATIVES AS MODULATORS OF G12D MUTANT KRAS USEFUL FOR THE TREATMENT OF CANCER Jazz Pharmaceuticals Ireland Ltd. (IE) 2026-03-18 EP disclosed
US-20260062425-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF GENENTECH INC (US) 2026-03-05 US disclosed
US-20260035378-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY NURIX THERAPEUTICS INC (US) 2026-02-05 US disclosed
US-20250339411-A1 GLP-1R AGONIST COMPOUND AND USE THEREOF CHONGQING PHARMACEUTICAL RES INSTITUTE CO LTD (CN) 2025-11-06 US disclosed
US-12419874-B2 GLP-1R agonist compound and use thereof CHONGQING PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) 2025-09-23 US disclosed
WO-2000001714-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed
US-5242903-A Enzyme inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed
US-5095006-A Enzyme inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0412350-A2 Renininhibitors, procedure for their preparation and use as medicaments BAYER AG (DE) 1991-02-13 EP disclosed
EP-0324993-A1 Sparsomicin (Sc-Rs) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (Sc-Rs) compounds Stichting Katholieke Universiteit (NL) 1989-07-26 EP disclosed
US-4837349-A Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1989-06-06 US disclosed
US-4820712-A Sparsomycin (SC-RS) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (SC-RS) compounds STICHTING KATHOLIEKE UNIVERSITEIT (NL) 1989-04-11 US disclosed
EP-0217243-A2 Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same SUNTORY LIMITED (JP) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062425-A1 AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF KRAS, NRAS, HRAS HSD17B10 1079/4885SMN1; SMN2 1998/4885NPC1 2732/4885
US-20260035378-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY BTK, PSMB2, PSMB1 HSD17B10 3641/4885SMN1; SMN2 2048/4885NPC1 1662/4885
US-20250339411-A1 GLP-1R AGONIST COMPOUND AND USE THEREOF GLP1R, GIPR, GPR119 HSD17B10 1667/4885SMN1; SMN2 2057/4885NPC1 707/4885
US-12419874-B2 GLP-1R agonist compound and use thereof GLP1R, GIPR, GPR119 HSD17B10 1667/4885SMN1; SMN2 2057/4885NPC1 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.