Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.43 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.43 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.43 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.43 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.43 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.43 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830341 | 0.88 | MAPT (0.40) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL8830373 | 0.88 | ROCK2 (0.40) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| Iodide SCHEMBL8830365 | 0.87 | ROCK2 (0.39) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| Iodide SCHEMBL8830348 | 0.86 | ROCK2 (0.40) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL8442775 | 0.83 | MEN1 (0.49) | ABCB1CTSSCTSKCTSBCTSL | |
| SCHEMBL7338218 | 0.78 | CTSS (0.45) | ABCB1CTSSCTSKCTSBCTSL | |
| SCHEMBL7304706 | 0.78 | ABCB1 (0.44) | ABCB1CTSSCTSKCTSBCTSL | |
| SCHEMBL7305886 | 0.77 | CTSS (0.45) | PSMB8PSMB5ABCB1CTSSCTSK | |
| SCHEMBL7301659 | 0.77 | CTSG (0.46) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL9215224 | 0.76 | REN (0.48) | ABCB1CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663297-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-09-02 | — | — | US | disclosed |