SCHEMBL88349

SCHEMBL88349

CC/C=C\C/C=C\CCO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
CYP19A1 P11511 4/20 0.54
PPARG P37231 3/20 0.54
OXER1 Q8TDS5 3/20 0.54
MAPT P10636 3/20 0.54
RXRA P19793 2/20 0.54
FFAR1 O14842 2/20 0.54
CNR1 P21554 2/20 0.52
PTGS1 P23219 4/20 0.50
F7 P08709 3/20 0.50
F3 P13726 3/20 0.50
PPARA Q07869 3/20 0.50
KMT2A Q03164 2/20 0.50
PPARD Q03181 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
NR1I2 O75469 2/20 0.47
PTGS2 P35354 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289360 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL18339353 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL88350 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL1245698 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL19920999 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL21052414 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL1245776 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL19921001 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL9155208 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
SCHEMBL290480 1.00 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191261-A1 PROCESS FOR MAKING FLAVOR AND FRAGRANT COMPOUNDS FIRMENICH SA (CH) 2024-06-13 US claimed
US-20240050337-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2024-02-15 US claimed
US-11864571-B2 Lucuma nervosa essence and lucuma nervosa aroma enhancer, preparation method and applications thereof SHANGHAI INSTITUTE OF TECHNOLOGY (CN) 2024-01-09 US claimed
EP-3613724-B1 PROCESS FOR PREPARING (E2,Z6)-2,6-NONADIENAL SHINETSU CHEMICAL CO (JP) 2023-06-07 EP claimed
CN-110857265-B Process for preparing (E2) -cis-6, 7-epoxy-2-nonenal 信越化学工业株式会社 2023-05-16 CN claimed
CN-110857264-B Process for preparing (E2, Z6) -2, 6-nonadienal 信越化学工业株式会社 2023-05-12 CN claimed
US-20210315243-A1 LUCUMA NERVOSA ESSENCE AND LUCUMA NERVOSA AROMA ENHANCER, PREPARATION METHOD AND APPLICATIONS THEREOF SHANGHAI INSTITUTE OF TECHNOLOGY (CN) 2021-10-14 US claimed
US-20210163994-A1 PROCESS FOR MAKING FLAVOR AND FRAGRANT COMPOUNDS FIRMENICH SA (CH) 2021-06-03 US claimed
WO-2021022834-A1 LUCUMA NERVOSA A. DC. ESSENTIAL OIL, ENHANCER, AND PREPARATION METHOD AND USE THEREFOR 上海应用技术大学 2021-02-11 WO claimed
US-10781194-B2 Process for preparing (E2)-cis-6,7-epoxy-2-nonenal SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-09-22 US claimed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US claimed
US-8128948-B1 Compositions and methods for attracting Anastrepha species THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2012-03-06 US claimed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US claimed
EP-1962792-A1 COSMETIC AGENTS HAVING INCREASED FRAGRANCE INTENSITY AND PERSISTENCE Henkel AG & Co. KGaA (DE) 2008-09-03 EP claimed
WO-2007068339-A1 COSMETIC AGENTS HAVING INCREASED FRAGRANCE INTENSITY AND PERSISTENCE HENKEL AG & CO. KGAA (DE) 2007-06-21 WO claimed
EP-1268819-B1 MUSKMELON (CUCUMIS MELO) HYDROPEROXIDE LYASE AND USES THEREOF FIRMENICH & CIE (CH) 2006-06-07 EP claimed
US-7037693-B2 Muskmelon (Cucumis melo) hydroperoxide lyase and uses thereof VANDERBILT UNIVERSITY (US) 2006-05-02 US claimed
EP-1268819-A2 MUSKMELON (CUCUMIS MELO) HYDROPEROXIDE LYASE AND USES THEREOF Firmenich S.A. (CH) 2003-01-02 EP claimed
US-20020098570-A1 Muskmelon (Cucumis melo) hydroperoxide lyase and uses thereof VANDERBILT UNIVERSITY 2002-07-25 US claimed
WO-2001073075-A2 MUSKMELON CUCUMIS MELO HYDROPEROXIDE LYASE AND USES THEREOF FIRMENICH S.A. (CH) 2001-10-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240050337-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS OR10J3, OR51E2, MAL2 ALDH1A1 27/4885CYP19A1 935/4885PPARG 3888/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 ALDH1A1 3134/4885CYP19A1 3936/4885PPARG 79/4885
US-10781194-B2 Process for preparing (E2)-cis-6,7-epoxy-2-nonenal NFE2L2, CYP2A6, CYP2J2 ALDH1A1 186/4885CYP19A1 18/4885PPARG 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.