Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | F7 | P08709 | 3/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289360 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL88350 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL1245698 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL19920999 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL21052414 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL88349 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL1245776 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL19921001 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL9155208 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT | |
| SCHEMBL290480 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP19A1PPARGOXER1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11958859-B2 | Use of pyridoxal acetal salts as water-triggered pro-fragrances | FLORIDA GULF COAST UNIVERSITY BOARD OF TRUSTEES (US) | 2024-04-16 | — | — | US | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-108601958-B | Pro-fragrance compositions | 爱客多有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3416729-A1 | PRO-FRAGRANCE COMPOSITION | Aqdot Limited (GB) | 2018-12-26 | — | — | EP | disclosed |
| EP-3368542-A2 | HIGH INTENSITY SWEETENERS | Senomyx, Inc. (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017141030-A1 | PRO-FRAGRANCE COMPOSITION | AQDOT LIMITED (GB) | 2017-08-24 | — | — | WO | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED | 2017-05-04 | — | — | US | disclosed |
| WO-2017075257-A2 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-04-06 | — | — | US | disclosed |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | SENOMYX INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | SENOMYX INC (US) | 2016-12-29 | — | — | US | disclosed |
| CN-105758961-A | Simulating preparation method for natural watermelon essence | 北京工商大学 | 2016-07-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CYP19A1 4650/4885PPARG 217/4885 |
| US-20170119032-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CYP19A1 4650/4885PPARG 217/4885 |
| US-20160376263-A1 | BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF | TAS2R5, TAS1R1, TAS2R1 | ALDH1A1 1490/4885CYP19A1 3584/4885PPARG 102/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CYP19A1 4650/4885PPARG 217/4885 |
| US-11958859-B2 | Use of pyridoxal acetal salts as water-triggered pro-fragrances | PLPBP, PNPO, ADH5 | ALDH1A1 394/4885CYP19A1 1630/4885PPARG 1468/4885 |
| US-20170087199-A1 | COMPOSITIONS FOR DELIVERING A COOLING SENSATION | TRPA1, PDE6G, PDE6D | ALDH1A1 1029/4885CYP19A1 577/4885PPARG 111/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CYP19A1 4650/4885PPARG 217/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | ALDH1A1 978/4885CYP19A1 4650/4885PPARG 217/4885 |
| US-20170096418-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | ALDH1A1 3880/4885CYP19A1 3947/4885PPARG 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.