Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 8/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 4/20 | 0.34 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835194 | 0.96 | HTR2C (0.46) | HTR2CDGAT1SOAT1IDO1DRD2 | |
| SCHEMBL8835268 | 0.88 | HTR2C (0.42) | HTR2CDGAT1SOAT1IDO1P2RY14 | |
| SCHEMBL8835301 | 0.86 | DGAT1 (0.33) | DGAT1SOAT1ESR2 | |
| SCHEMBL8835367 | 0.85 | ESR2 (0.34) | DGAT1DRD2GRM2HTR1ADRD3 | |
| SCHEMBL8456906 | 0.85 | HTR2C (0.46) | HTR2CDGAT1SOAT1IDO1P2RY14 | |
| SCHEMBL8835095 | 0.84 | HTR2C (0.45) | HTR2CDGAT1SOAT1IDO1DRD2 | |
| SCHEMBL8835312 | 0.84 | L3MBTL1 (0.40) | P2RY14GRM2CHRM2KIF11CHRM1 | |
| SCHEMBL8835613 | 0.83 | KIF11 (0.41) | DGAT1SOAT1KIF11 | |
| SCHEMBL8835639 | 0.81 | HTR2C (0.42) | HTR2CDGAT1SOAT1IDO1DRD2 | |
| SCHEMBL8835145 | 0.80 | ESR2 (0.37) | DRD2GRM2DRD5DRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |