SCHEMBL8837449

SCHEMBL8837449

CC(O)COC(C)COP(=O)(O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
ANPEP P15144 2/20 0.47
LAP3 P28838 2/20 0.47
LMNA P02545 1/20 0.46
SRC P12931 1/20 0.42
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837426 0.83 LMNA (0.46) ALDH1A1ANPEPLAP3LMNASRC
SCHEMBL4630199 0.82 ANPEP (0.54) ALDH1A1ANPEPLAP3LMNASRC
SCHEMBL11234177 0.79 ANPEP (0.55) ALDH1A1ANPEPLAP3SRCPOLB
SCHEMBL28439359 0.79 ALDH1A1 (0.46) ALDH1A1ANPEPLAP3SRCL3MBTL1
SCHEMBL428419 0.76 ALDH1A1 (0.51) ALDH1A1ANPEPLAP3LMNASRC
SCHEMBL26207079 0.75 MTNR1A (0.49) ALDH1A1ANPEPLAP3LMNASRC
SCHEMBL11714352 0.75 SRC (0.50) ALDH1A1ANPEPLAP3SRCPOLB
SCHEMBL11787681 0.75 SRC (0.50) ALDH1A1ANPEPLAP3SRCPOLB
SCHEMBL872625 0.75 LMNA (0.75) ALDH1A1LMNAL3MBTL1CYP2C19
SCHEMBL27675562 0.75 ALDH1A1 (0.50) ALDH1A1ANPEPLAP3LMNASRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3476876-B1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2023-08-09 EP disclosed
EP-3476876-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2019-05-01 EP disclosed
US-9751063-B2 Emulsion compositions and applications therefor MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-09-05 US disclosed
EP-3083738-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2016-10-26 EP disclosed
EP-3079777-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR Momentive Performance Materials Inc. (US) 2016-10-19 EP disclosed
US-9321878-B2 Process for the preparation of silylated polyurethane polymers using titanium-containing and zirconium-containing catalysts MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-04-26 US disclosed
US-9102779-B2 Method for producing oxidation discoloration resistant polyurethane foam WM. T. BURNETT IP, LLC (US) 2015-08-11 US disclosed
WO-2015095029-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-25 WO disclosed
WO-2015089035-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-18 WO disclosed
US-20150166719-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-18 US disclosed
US-20150157996-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR MOMENTIVE PERFORMANCE MATERIALS INC. 2015-06-11 US disclosed
US-20140039077-A1 Method For Producing Oxidation Discoloration Resistant Polyurethane Foam WM. T. BURNETT IP, LLC (US) 2014-02-06 US disclosed
US-8557946-B1 Oxidation discoloration resistant polyurethane foam WM. T. BURNETT IP, LLC (US) 2013-10-15 US disclosed
US-5633420-A BORON TRIFLUORIDE AND PHOSPHORUS PROMOTER AMOCO CORPORATION (US) 1997-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157996-A1 EMULSION COMPOSITIONS AND APPLICATIONS THEREFOR POLR1C, POLQ, POLH ALDH1A1 3117/4885ANPEP 2491/4885LAP3 3451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.