Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4466817 | 0.89 | MAPT (0.43) | MAPTLMNAMEN1KMT2ATP53 | |
| SCHEMBL12758951 | 0.85 | HRH3 (0.56) | MAPTLMNAMEN1KMT2ATDP1 | |
| SCHEMBL8837552 | 0.81 | LMNA (0.61) | MAPTLMNAMEN1KMT2ALOXL2 | |
| SCHEMBL11354778 | 0.80 | GPR84 (0.44) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL8801068 | 0.77 | GPR84 (0.51) | MAPTLMNAMEN1KMT2ATP53 | |
| SCHEMBL8799883 | 0.73 | HTR1A (0.48) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL866136 | 0.73 | LOXL2 (0.72) | MAPTLMNAMEN1KMT2ALOXL2 | |
| SCHEMBL650217 | 0.73 | MAPT (0.86) | MAPTLMNAMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL9461139 | 0.72 | MAPT (0.51) | MAPTLMNAMEN1KMT2ATP53 | |
| SCHEMBL18669052 | 0.70 | CASP3 (0.65) | MAPTMEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582771-B2 | Process for the synthesis of cPLA2 inhibitors | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-7582771-B2 | Process for the synthesis of cPLA2 inhibitors | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050049296-A1 | Process for the synthesis of cPLA2 inhibitors | WYETH (US) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049296-A1 | Process for the synthesis of cPLA2 inhibitors | PLA2G12A, ACOX3, CPA2 | MAPT 4856/4885LMNA 1215/4885MEN1 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.