SCHEMBL8838286

SCHEMBL8838286

CCCCCCCCCCCCOC(=O)CCN(O)C1CC(C)(C)N(OCCCCCCCC)C(C)(C)C1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.41
DNM1 Q05193 1/20 0.40
HTR2C P28335 1/20 0.39
NAAA Q02083 1/20 0.39
DGKA P23743 1/20 0.39
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
PRKCA P17252 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8838285 1.00 EPHX2 (0.41) EPHX2DNM1HTR2CNAAADGKA
SCHEMBL8838269 0.91 KDM5A (0.40) EPHX2DNM1
SCHEMBL8917970 0.88 KDM5A (0.36) EPHX2
SCHEMBL8838281 0.85 EPHX2 (0.30) EPHX2
SCHEMBL8533073 0.78 KDM5A (0.39) EPHX2DNM1
SCHEMBL8917966 0.78 NAAA (0.40) EPHX2DNM1NAAADGKA
SCHEMBL9351971 0.77 EPHX2 (0.35) EPHX2NAAA
SCHEMBL9526524 0.77 ACE2 (0.34) EPHX2
SCHEMBL9351981 0.77 EPHX2 (0.36) EPHX2DNM1NAAADGKA
SCHEMBL8838296 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552464-A RADIATION AND HEAT RESISTANT POLYMERS WITH DERIVATIVES OF TETRAMETHYLPIPERIDINE AND HYDROXYLAMINES CIBA-GEIGY CORPORATION (US) 1996-09-03 US claimed
EP-0427672-B1 POLYMER STABILIZERS CONTAINING BOTH HINDERED AMINE AND HYDROXYLAMINE MOIETIES CIBA-GEIGY AG (CH) 1993-09-29 EP claimed
US-5202441-A Heat resistance, photostability CIBA-GEIGY CORPORATION (US) 1993-04-13 US claimed
EP-0427672-A1 Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY AG (CH) 1991-05-15 EP claimed
US-5668198-A Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY CORPORATION (US) 1997-09-16 US disclosed
US-5668199-A Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY CORPORATION (US) 1997-09-16 US disclosed
US-5574162-A CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-11-12 US disclosed
US-5552464-A RADIATION AND HEAT RESISTANT POLYMERS WITH DERIVATIVES OF TETRAMETHYLPIPERIDINE AND HYDROXYLAMINES CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5442071-A Photostability CIBA-GEIGY CORPORATION (US) 1995-08-15 US disclosed
US-5410047-A A 2-hydroxyamino-4,6-substituted triazine as light stabilizers for polymers; radiation resistance, oxidation resistance, discoloration inhibition CIBA-GEIGY CORPORATION (US) 1995-04-25 US disclosed
US-5359069-A Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-10-25 US disclosed
US-5286865-A Contain reactive functional group which can be chemically attached to selected polymer substrates CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
EP-0427672-B1 POLYMER STABILIZERS CONTAINING BOTH HINDERED AMINE AND HYDROXYLAMINE MOIETIES CIBA-GEIGY AG (CH) 1993-09-29 EP disclosed
US-5202441-A Heat resistance, photostability CIBA-GEIGY CORPORATION (US) 1993-04-13 US disclosed
US-5145893-A Photostability CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
EP-0427672-A1 Polymer stabilizers containing both hindered amine and hydroxylamine moieties CIBA-GEIGY AG (CH) 1991-05-15 EP disclosed
EP-0389419-A1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed