SCHEMBL8917966

SCHEMBL8917966

CCCCCCCCON1C(C)(C)CC(N(O)OC(=O)CC)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.40
EPHX2 P34913 8/20 0.33
DNM1 Q05193 1/20 0.32
DGKA P23743 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
RAD52 P43351 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351971 0.81 EPHX2 (0.35) NAAAEPHX2HCAR2
SCHEMBL9226072 0.80 HCAR2 (0.35) NAAAEPHX2HCAR2
SCHEMBL8838281 0.79 EPHX2 (0.30) EPHX2
SCHEMBL8838285 0.78 EPHX2 (0.41) NAAAEPHX2DNM1DGKA
SCHEMBL8838269 0.78 KDM5A (0.40) EPHX2DNM1
SCHEMBL8838286 0.78 EPHX2 (0.41) NAAAEPHX2DNM1DGKA
SCHEMBL9351981 0.78 EPHX2 (0.36) NAAAEPHX2DNM1DGKA
SCHEMBL8917970 0.78 KDM5A (0.36) EPHX2
SCHEMBL8917972 0.77 NAAA (0.40) NAAAEPHX2
SCHEMBL9352000 0.76 EPHX2 (0.40) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679794-A ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1997-10-21 US disclosed