SCHEMBL9351971

SCHEMBL9351971

CCCCCCCCON1C(C)(C)CC(N(C(=O)C(=O)N(C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 7/20 0.35
NAAA Q02083 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CES2 O00748 1/20 0.33
EPHX1 P07099 1/20 0.32
GBA2 Q9HCG7 1/20 0.32
TSHR P16473 2/20 0.31
ACHE P22303 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352000 0.88 EPHX2 (0.40) EPHX2EPHX1ACHE
SCHEMBL2461222 0.88 EPHX2 (0.30) EPHX2
SCHEMBL9351981 0.88 EPHX2 (0.36) EPHX2NAAA
SCHEMBL9226072 0.84 HCAR2 (0.35) EPHX2NAAAHCAR2CES2
SCHEMBL2462031 0.82 DGKA (0.34) EPHX2NAAACES2
SCHEMBL8917966 0.81 NAAA (0.40) EPHX2NAAAHCAR2
SCHEMBL27541044 0.81 EPHX2 (0.31) EPHX2
SCHEMBL8838281 0.80 EPHX2 (0.30) EPHX2
SCHEMBL13714975 0.79 EPHX2 (0.32) EPHX2
SCHEMBL8917970 0.79 KDM5A (0.36) EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed