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SCHEMBL9351981

SCHEMBL9351981

CCCCCCCCON1C(C)(C)CC(N(C(=O)CCCCCCCCC(=O)N(C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 10/20 0.36
▸ DGKA P23743 1/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ NAAA Q02083 2/20 0.33
▸ DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2462031 0.95 DGKA (0.34) EPHX2DGKACNR2NAAADNM1
SCHEMBL2457690 0.92 EPHX2 (0.33) EPHX2CNR2
SCHEMBL2455260 0.92 EPHX2 (0.35) EPHX2DGKACNR2NAAA
SCHEMBL9351971 0.88 EPHX2 (0.35) EPHX2NAAA
SCHEMBL9352000 0.82 EPHX2 (0.40) EPHX2
SCHEMBL9226072 0.81 HCAR2 (0.35) EPHX2NAAA
SCHEMBL13714975 0.79 EPHX2 (0.32) EPHX2DNM1
SCHEMBL8917970 0.79 KDM5A (0.36) EPHX2
SCHEMBL8917966 0.78 NAAA (0.40) EPHX2DGKANAAADNM1
SCHEMBL13435126 0.77 NAAA (0.52) EPHX2DGKANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 — — EP claimed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 — — US claimed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 — — EP claimed
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 — — EP disclosed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 — — US disclosed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 — — EP disclosed