Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696589 | 1.00 | KCNH3 (0.42) | KCNH3MEN1KMT2AKIF11DUT | |
| SCHEMBL30226689 | 0.75 | LMNA (0.48) | KCNH3MEN1KMT2ATSHR | |
| SCHEMBL9390758 | 0.74 | KCNH3 (0.41) | KCNH3MEN1KMT2A | |
| SCHEMBL31259093 | 0.73 | KIF11 (0.43) | MEN1KMT2AKIF11SLC6A1 | |
| SCHEMBL9223044 | 0.72 | MGLL (0.45) | — | |
| SCHEMBL9029731 | 0.72 | SMYD2 (0.43) | KCNH3 | |
| SCHEMBL16225349 | 0.72 | SMYD2 (0.43) | KCNH3 | |
| SCHEMBL3685687 | 0.71 | MAOB (0.49) | KCNH3 | |
| SCHEMBL7899581 | 0.71 | MAOB (0.49) | KCNH3 | |
| SCHEMBL7906013 | 0.71 | MAOB (0.49) | KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656617-A | ANTIVIRAL AGENT | MEDIVIR AB (SE) | 1997-08-12 | — | — | US | disclosed |
| US-5565461-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | MEDIVIR AB (SE) | 1996-10-15 | — | — | US | disclosed |
| US-5284837-A | Viricides | MEDIVIR AB (SE) | 1994-02-08 | — | — | US | disclosed |
| EP-0343133-B1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | Medivir Aktiebolag (SE) | 1992-04-08 | — | — | EP | disclosed |
| WO-1989010923-A1 | DERIVATIVES OF PURINE, PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION | MEDIVIR AB (SE) | 1989-11-16 | — | — | WO | disclosed |