SCHEMBL8840487

SCHEMBL8840487

COCc1nccc(N(OCc2ccccc2)C2(c3ccccc3)CCCCC2)c1Br

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 6/20 0.34
OPRM1 P35372 5/20 0.34
SLC6A5 Q9Y345 1/20 0.31
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8840422 0.88 OPRM1 (0.34) OPRL1OPRM1SLC6A5OPRK1
SCHEMBL8840577 0.82
SCHEMBL9035779 0.82 OPRM1 (0.34) OPRL1OPRM1SLC6A5OPRK1
SCHEMBL8840459 0.80 OPRM1 (0.32) OPRL1OPRM1OPRK1
SCHEMBL9034632 0.79 OPRM1 (0.36) OPRL1OPRM1SLC6A5OPRK1
SCHEMBL8840381 0.79 OPRM1 (0.34) OPRL1OPRM1OPRK1
SCHEMBL8840558 0.79 MAPT (0.33) OPRL1OPRM1
SCHEMBL8840544 0.79 MEN1 (0.36) OPRL1OPRM1SLC6A5OPRK1
SCHEMBL8840404 0.79 TSHR (0.36) OPRL1OPRM1
SCHEMBL8840413 0.78 OPRM1 (0.37) OPRL1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 US disclosed