Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840404 | 0.97 | TSHR (0.36) | MEN1KMT2ATSHRCYP1A2CYP2C19 | |
| SCHEMBL8840459 | 0.93 | OPRM1 (0.32) | OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL8840413 | 0.92 | OPRM1 (0.37) | OPRM1OPRL1 | |
| SCHEMBL8840422 | 0.90 | OPRM1 (0.34) | OPRD1OPRK1OPRM1OPRL1SLC6A5 | |
| SCHEMBL8840440 | 0.88 | — | — | |
| SCHEMBL8840558 | 0.88 | MAPT (0.33) | OPRM1OPRL1 | |
| SCHEMBL9035779 | 0.86 | OPRM1 (0.34) | OPRK1TSHROPRM1OPRL1SLC6A5 | |
| SCHEMBL9033924 | 0.82 | RORC (0.33) | OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL8840419 | 0.82 | RORC (0.32) | ALDH1A1LMNA | |
| SCHEMBL8840449 | 0.80 | OPRM1 (0.31) | OPRM1OPRL1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |