Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840422 | 0.92 | OPRM1 (0.34) | OPRM1OPRL1SLC6A5OPRK1 | |
| SCHEMBL8840459 | 0.88 | OPRM1 (0.32) | OPRM1OPRL1OPRK1 | |
| SCHEMBL9034632 | 0.88 | OPRM1 (0.36) | OPRM1OPRL1SLC6A5OPRK1 | |
| SCHEMBL8840449 | 0.87 | OPRM1 (0.31) | OPRM1OPRL1SLC6A5 | |
| SCHEMBL8840544 | 0.86 | MEN1 (0.36) | OPRM1OPRL1SLC6A5TSHROPRK1 | |
| SCHEMBL8840404 | 0.86 | TSHR (0.36) | OPRM1OPRL1TSHR | |
| SCHEMBL8840381 | 0.85 | OPRM1 (0.34) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8840558 | 0.84 | MAPT (0.33) | OPRM1OPRL1 | |
| SCHEMBL9033924 | 0.84 | RORC (0.33) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8840413 | 0.83 | OPRM1 (0.37) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |