Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840422 | 0.90 | OPRM1 (0.34) | OPRM1OPRL1 | |
| SCHEMBL8840459 | 0.90 | OPRM1 (0.32) | MAPTOPRM1OPRL1 | |
| SCHEMBL8840440 | 0.88 | — | — | |
| SCHEMBL8840544 | 0.88 | MEN1 (0.36) | OPRM1OPRL1 | |
| SCHEMBL8840404 | 0.88 | TSHR (0.36) | MAPTOPRM1OPRL1 | |
| SCHEMBL8840413 | 0.86 | OPRM1 (0.37) | OPRM1OPRL1 | |
| SCHEMBL9035779 | 0.84 | OPRM1 (0.34) | OPRM1OPRL1 | |
| SCHEMBL8840449 | 0.80 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL8840487 | 0.79 | OPRL1 (0.34) | OPRM1OPRL1 | |
| SCHEMBL9033924 | 0.79 | RORC (0.33) | MAPTOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |