Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8841001 | 0.88 | BCHE (0.31) | ACHEBCHEEP300HDAC6MAPT | |
| SCHEMBL9411277 | 0.82 | GABRP (0.38) | ACHEBCHEGAAEP300HDAC6 | |
| SCHEMBL8840975 | 0.82 | NPC1 (0.32) | ACHEBCHEGAAEP300HDAC6 | |
| SCHEMBL8840946 | 0.81 | EP300 (0.33) | ACHEBCHEGAAEP300HDAC6 | |
| SCHEMBL9738208 | 0.81 | GAA (0.34) | GAAEP300HDAC6MAPTPOLB | |
| SCHEMBL8840997 | 0.78 | KMT2A (0.33) | GAAEP300HDAC6MAPTPOLB | |
| SCHEMBL8840999 | 0.78 | ACHE (0.47) | ACHEBCHEGAAHTR1AMAPT | |
| SCHEMBL8840963 | 0.75 | GABRP (0.47) | ACHEBCHEEP300HDAC6MAPT | |
| SCHEMBL8840969 | 0.75 | MAPT (0.38) | ACHEBCHEEP300HDAC6MAPT | |
| SCHEMBL10365809 | 0.74 | ACHE (0.38) | ACHEGAAMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | claimed |
| US-5597918-A | ANXIOLYTIC AGENTS, SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |