SCHEMBL8841230

SCHEMBL8841230

O=C1CC2C(CC3C(=O)OC(=O)C32)C(=O)O1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
PPM1B O75688 1/20 0.34
LMNA P02545 1/20 0.34
PPP1CC P36873 1/20 0.34
TFPI2 P48307 1/20 0.34
RAB9A P51151 1/20 0.34
PPP5C P53041 1/20 0.34
PPP1CA P62136 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21241534 1.00 KDM4E (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL215947 1.00 KDM4E (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20968363 1.00 KDM4E (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL19241223 1.00 KDM4E (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL21609706 1.00 KDM4E (0.34) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL12197536 0.85
SCHEMBL21322463 0.82
SCHEMBL18179375 0.81 ALDH1A1 (0.30)
SCHEMBL10361730 0.81 KDM4E (0.32) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL21118044 0.79 KDM4E (0.31) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021132279-A1 RESIN COMPOSITION AND FILM 株式会社カネカ 2021-07-01 WO disclosed
EP-3125033-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2021-06-02 EP disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
US-10782566-B2 Liquid crystal display device JNC CORPORATION (JP) 2020-09-22 US disclosed
EP-3179303-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-04-01 EP disclosed
US-10573834-B2 Coating liquid for gate insulating film, gate insulating film and organic transistor NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-02-25 US disclosed
US-10435627-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-10-08 US disclosed
US-10423033-B2 Method for producing liquid crystal alignment film and liquid crystal display element using same DIC CORPORATION (JP) 2019-09-24 US disclosed
EP-3133136-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-08-07 EP disclosed
EP-3163368-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-06-26 EP disclosed
US-20080085361-A1 Inkjet ink CHISSO CORPORATION 2008-04-10 US disclosed
EP-1894977-A1 Inkjet ink Chisso Corporation (JP) 2008-03-05 EP disclosed
US-20080003381-A1 Overcoat film composition, color filter substrate, and liquid crystal display element CHISSO CORPORATION 2008-01-03 US disclosed
US-20080003381-A1 Overcoat film composition, color filter substrate, and liquid crystal display element CHISSO CORPORATION 2008-01-03 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed
US-20070232780-A1 PHOTO-ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2007-10-04 US disclosed
US-20070213502-A1 Composition for forming insulating layer and insulating film JNC CORPORATION (JP) 2007-09-13 US disclosed
US-20070213502-A1 Composition for forming insulating layer and insulating film JNC CORPORATION (JP) 2007-09-13 US disclosed
US-5596435-A Liquid crystal display device KABUSHIKI KAISHA TOSHIBA (JP) 1997-01-21 US disclosed
US-5477360-A Liquid crystal display device KABUSHIKI KAISHA TOSHIBA (JP) 1995-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 KDM4E 1412/4885GMNN 2665/4885PPM1B 1057/4885
US-20080085361-A1 Inkjet ink MAOA, MAOB, AADAT KDM4E 158/4885GMNN 2215/4885PPM1B 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.