Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | GLUL | P15104 | 1/20 | 0.32 |
| ▸ | OTC | P00480 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842798 | 0.94 | FOLH1 (0.34) | FOLH1BHMTNAALAD2GLUL | |
| SCHEMBL8842667 | 0.88 | FOLH1 (0.38) | FOLH1NAALAD2GLULGRIN2DGRIN3B | |
| SCHEMBL8843565 | 0.82 | CPB2 (0.41) | FOLH1BHMTGLULLMNABLM | |
| SCHEMBL8842970 | 0.82 | FDPS (0.50) | — | |
| SCHEMBL9116738 | 0.82 | FOLH1 (0.41) | FOLH1BHMTNAALAD2GLULOTC | |
| SCHEMBL8842630 | 0.81 | FDPS (0.52) | — | |
| SCHEMBL8844113 | 0.81 | GSR (0.47) | FOLH1BHMTLMNABLM | |
| SCHEMBL8844107 | 0.79 | GSR (0.46) | FOLH1BHMTMEN1LMNABLM | |
| SCHEMBL8842649 | 0.79 | ALDH1A1 (0.37) | FOLH1BHMTNAALAD2GRIN2DGRIN3B | |
| SCHEMBL8844273 | 0.79 | GSR (0.46) | FOLH1BHMTMEN1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683994-A | BONE DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5683994-A | BONE DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-04 | — | — | US | disclosed |