Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | GHSR | Q92847 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843072 | 0.78 | NPC1 (0.43) | HDAC6GHSRALDH1A1POLBRAB9A | |
| SCHEMBL8843372 | 0.74 | DAGLA (0.41) | HDAC6HDAC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8844341 | 0.72 | LMNA (0.43) | HDAC6HDAC1ALDH1A1POLBHDAC3 | |
| SCHEMBL28264986 | 0.70 | SIGMAR1 (0.58) | ALDH1A1POLBMEN1KMT2ARAB9A | |
| SCHEMBL6320472 | 0.69 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL8843638 | 0.68 | HIF1A (0.43) | HDAC6HDAC1ALDH1A1POLBHDAC3 | |
| SCHEMBL8843575 | 0.68 | NPC1 (0.45) | HDAC6HDAC1GHSRALDH1A1POLB | |
| SCHEMBL4783916 | 0.68 | ALDH1A1 (0.40) | ALDH1A1RAB9A | |
| SCHEMBL7348202 | 0.67 | ALDH1A1 (0.56) | ALDH1A1RAB9A | |
| SCHEMBL7348196 | 0.67 | ALDH1A1 (0.56) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |