Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409003 | 0.79 | CNR2 (0.49) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL15219430 | 0.75 | LMNA (0.69) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL15254011 | 0.73 | ALDH1A1 (0.40) | LMNAALDH1A1SMN1; SMN2TP53TDP1 | |
| SCHEMBL10674476 | 0.72 | DAGLA (0.40) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8843368 | 0.72 | DAGLA (0.44) | LMNAALDH1A1TP53POLBMEN1 | |
| SCHEMBL8843372 | 0.72 | DAGLA (0.41) | HDAC1HDAC6LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3334525 | 0.72 | SLC9A1 (0.68) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4842993 | 0.71 | MEN1 (0.44) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| Benzene SCHEMBL11697595 | 0.71 | MEN1 (0.78) | MAPTMEN1KMT2ATDP1 | |
| SCHEMBL1654 | 0.71 | MEN1 (0.78) | MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414068-B2 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2008-08-19 | — | — | US | disclosed |
| US-20060035948-A1 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035948-A1 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | TH, TNNI3, NOS3 | HDAC1 403/4885HDAC6 267/4885MAPT 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.