Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843565 | 0.83 | CPB2 (0.41) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8844113 | 0.78 | GSR (0.47) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8844273 | 0.77 | GSR (0.46) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8844107 | 0.77 | GSR (0.46) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8843499 | 0.76 | GABRR1 (0.40) | GABRR1LMNACYP3A4NFKB1BLM | |
| SCHEMBL8843633 | 0.72 | ANPEP (0.41) | LMNABLMGABBR2GABBR1ALDH1A1 | |
| SCHEMBL8843656 | 0.71 | ALDH1A1 (0.46) | LAP3ALDH1A1TDP1SLC1A3SLC1A2 | |
| SCHEMBL8843138 | 0.71 | SLC1A3 (0.36) | BLMLAP3ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8842970 | 0.69 | FDPS (0.50) | LAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9117263 | 0.69 | GSR (0.48) | CPB2LMNACYP3A4NFKB1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |