Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239591 | 0.88 | ALOX15 (0.49) | ALOX15ALOX12MEN1KMT2AMAPT | |
| SCHEMBL5485044 | 0.79 | ALOX5 (0.55) | ALOX5PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL29493070 | 0.79 | ALOX5 (0.55) | ALOX5PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL8843771 | 0.76 | PDE4A (0.52) | KMT2AMAPTHPGDMAPK1LMNA | |
| SCHEMBL8843736 | 0.76 | TSHR (0.55) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL14515226 | 0.74 | CSNK2A2 (0.53) | ALOX5PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL3693339 | 0.73 | MAOB (0.67) | ALOX5PTGS1PTGS2NR3C1ALOX15 | |
| SCHEMBL8843729 | 0.73 | HTT (0.54) | ALOX5PTGS1PTGS2ALOX15ALOX12 | |
| SCHEMBL11571527 | 0.73 | FOS (0.80) | ALOX5PTGS1FOSTTRJUN | |
| SCHEMBL4386820 | 0.71 | MAOB (0.64) | ALOX5PTGS1PTGS2NR3C1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |