Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718374 | 0.86 | CHRNA7 (0.55) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B | |
| SCHEMBL6221063 | 0.85 | ADRA2A (0.57) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6217940 | 0.83 | ADRA2A (0.55) | CHRNA7ADRA2AADRA2BADRA2CMEN1 | |
| SCHEMBL2852781 | 0.81 | MAPT (0.48) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL23133806 | 0.81 | DRD2 (0.54) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B | |
| SCHEMBL6973198 | 0.81 | ADRA2A (0.65) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B | |
| SCHEMBL27269583 | 0.78 | — | — | |
| SCHEMBL23340098 | 0.77 | ADRA2A (0.54) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B | |
| SCHEMBL460139 | 0.76 | ADRA2A (0.58) | SIGMAR1CHRNA7ADRA2AADRA2BADRA2C | |
| SCHEMBL5247341 | 0.75 | DRD2 (0.51) | DRD2SIGMAR1CHRNA7ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696268-A | REACTING N-ACYLAMINO ACID DERIVATIVE WITH OPTICALLY ACTIVE ENAMINE DERIVATIVE, REACTING PRODUCT WITH AMMONIA OR AMMONIUM SALT | FUJIREBIO INC. (JP) | 1997-12-09 | — | — | US | claimed |