Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL218519 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3692124 | 0.72 | GABRA1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL31414081 | 0.72 | GABRA1 (0.30) | — | |
| SCHEMBL8844570 | 0.70 | LMNA (0.31) | LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL8164426 | 0.63 | BRD4 (0.33) | — | |
| SCHEMBL4650959 | 0.62 | LMNA (0.37) | LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL1453706 | 0.60 | LMNA (0.36) | LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL1452774 | 0.59 | LMNA (0.35) | LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL27493066 | 0.56 | LMNA (0.42) | LMNATRPA1PTGS1CACNA1C | |
| SCHEMBL19126163 | 0.55 | LMNA (0.40) | LMNATRPA1PTGS1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696213-A | HEATING IN PRESENCE OF A CATALYST SYSTEM | EXXON CHEMICAL PATENTS INC. (US) | 1997-12-09 | — | — | US | disclosed |