Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844633 | 1.00 | USP2 (0.42) | USP2ALDH1A1BCHESMN1; SMN2MEN1 | |
| SCHEMBL30642653 | 0.84 | MT-CO2 (0.52) | ALDH1A1MEN1KMT2ALMNAGAA | |
| SCHEMBL13595113 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAMAPTGAA | |
| SCHEMBL13594983 | 0.79 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11266599 | 0.72 | BCHE (0.58) | USP2ALDH1A1BCHESMN1; SMN2MEN1 | |
| SCHEMBL11252258 | 0.69 | USP2 (0.47) | USP2ALDH1A1BCHESMN1; SMN2MEN1 | |
| SCHEMBL11251034 | 0.69 | KMT2A (0.59) | USP2ALDH1A1BCHESMN1; SMN2MEN1 | |
| SCHEMBL29688496 | 0.68 | MT-CO2 (0.68) | USP2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10074427 | 0.66 | CYP2C19 (0.33) | — | |
| SCHEMBL22450066 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661014-A | Chiral compounds and their resolution synthesis using enantioselective esterases | CHIROSCIENCE LIMITED (GB) | 1997-08-26 | — | — | US | disclosed |