Styrene

Styrene

SCHEMBL327555

C=CC(=O)O.C=CCOC(=O)C(=C)C=CC#N.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
MAPT P10636 5/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
GAA P10253 1/20 0.37
PTP4A3 O75365 2/20 0.36
PTP4A1 Q93096 2/20 0.36
CASP1 P29466 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 7/20 0.34
TSHR P16473 2/20 0.34
HSD17B10 Q99714 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
PKM P14618 1/20 0.34
APP P05067 1/20 0.34
GLA P06280 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1255712 0.96 CYP3A4 (0.40) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL7698100 0.86 MAPT (0.40) CYP3A4MAPTMEN1KMT2AMAPK1
SCHEMBL17746697 0.85 CASP1 (0.41) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL3958178 0.84 KDM4E (0.39) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL8844775 0.84 KMT2A (0.48) MAPTMEN1KMT2AMAPK1KDM4E
Styrene SCHEMBL327472 0.83 CYP3A4 (0.44) CYP3A4MAPTMEN1KMT2AMAPK1
SCHEMBL8047550 0.82 MAPT (0.39) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL4566873 0.81 CYP3A4 (0.39) CYP3A4MAPTMEN1KMT2AMAPK1
Styrene SCHEMBL327788 0.81 CYP3A4 (0.38) CYP3A4MAPTMEN1KMT2AMAPK1
Acrylonitrile SCHEMBL9067820 0.80 CYP3A4 (0.44) CYP3A4MAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10358563-B2 Core-shell metal nanoparticle composite XEROX CORPORATION (US) 2019-07-23 US disclosed
US-20170233535-A1 CORE-SHELL METAL NANOPARTICLE COMPOSITE Genesee Valley Innovations, LLC 2017-08-17 US disclosed
US-9718970-B2 Core-shell metal nanoparticle composite XEROX CORPORATION (US) 2017-08-01 US disclosed
US-20160215104-A1 CORE-SHELL METAL NANOPARTICLE COMPOSITE Genesee Valley Innovations, LLC 2016-07-28 US disclosed
US-9164410-B2 Toner compositions for single component development system XEROX CORPORATION (US) 2015-10-20 US disclosed
US-9075329-B2 Emulsion aggregation toners with improved particle size distribution XEROX CORPORATION (US) 2015-07-07 US disclosed
US-9023567-B2 Polymerized charge enhanced spacer particle XEROX CORPORATION (US) 2015-05-05 US disclosed
US-8986917-B2 Toner composition having improved charge characteristics and additive attachment XEROX CORPORATION (US) 2015-03-24 US disclosed
US-20150004536-A1 TONER COMPOSITIONS FOR SINGLE COMPONENT DEVELOPMENT SYSTEM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2015-01-01 US disclosed
US-8889583-B2 Catalyst production XEROX CORPORATION (US) 2014-11-18 US disclosed
EP-1832606-B1 Toner composition and methods XEROX CORP (US) 2009-07-29 EP disclosed
US-7541126-B2 Toner composition XEROX CORPORATION (US) 2009-06-02 US disclosed
US-7476480-B2 Processes for producing toner by treatment with enzyme XEROX CORPORATION (US) 2009-01-13 US disclosed
US-20070248902-A1 Toner composition having dual wax XEROX CORPORATION 2007-10-25 US disclosed
EP-1832606-A1 toner composition and methods Xerox Corporation (US) 2007-09-12 EP disclosed
US-20070207400-A1 Toner composition and methods XEROX CORPORATION 2007-09-06 US disclosed
US-20070190441-A1 Toner composition XEROX CORPORATION 2007-08-16 US disclosed
US-20070134579-A1 Processes for producing toner by treatment with enzyme XEROX CORPORATION 2007-06-14 US disclosed
US-20070134576-A1 Toner composition XEROX CORPORATION 2007-06-14 US disclosed
US-20070037086-A1 Toner composition XEROX CORPORATION 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233535-A1 CORE-SHELL METAL NANOPARTICLE COMPOSITE PCBP1, PUF60, SEPTIN9 CYP3A4 4136/4885MAPT 216/4885MEN1 1447/4885
US-20160215104-A1 CORE-SHELL METAL NANOPARTICLE COMPOSITE PCBP1, PUF60, SEPTIN9 CYP3A4 4136/4885MAPT 216/4885MEN1 1447/4885
US-10358563-B2 Core-shell metal nanoparticle composite PCBP1, PUF60, SEPTIN9 CYP3A4 4136/4885MAPT 216/4885MEN1 1447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.